FERTILIZATION

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 FERTILIZATION:- 

Fertilization is the process of fusion of the spermatozoa with the mature ovum.

TWO PURPOSE:- 

(1) To start the embryonic development of the egg.

(2) To restore the chromosome number of species.

Always fertilization occurs in the ampullary parts of the uterine cavity.(Fallopion Tube)

Fertilization life spam of oocyte range    12 To 24 Hrs.

sperm range     48 To 72 Hrs.

Ovum      +      Sperm       →                    Zygote

(22+x)     +    (22+x) (44+xx)

(22+x)     +         (22+y) (44+xy)

or

(23x)       +        (23x) →            (46xx)

(23x)       +        (22y)  (46xy)

IMPORTANTS EVENTS FOLLING FERTILIZATION:-

Fertilization (0-15 From LMP) 0 hrs

2 cell stage (Blastomers)-30 Hrs

4 cell stage  40-50 Hrs 2 din 

12 cell stage  72 Hrs 3 din 

16 cell stage  (Morulla)  - 96hrs  4 day 

Enter morulla in uterine cavity 4 day 

5th day blastocyst formrtion  4 day 

Zona pellucide disappear 4-5 days 

Blastocyst attachment to endometrial surface 5-6 days.

Differentition of cyto end synciotrophoblast 6-7 days.

Interstitial implantation 7-9 days 

Synthesis of HCG by synctiotrophoblast - 10 days

Implantation completes  10-11days

Primary villi- 13th days 

Secondary villi -16th days

Tertary villi -21th days

Placenta  fully established formed - 21 days 

Feto- placental cirulation establishment (Fetal Heart)- 21-22days

Internal gonards formed -8 weeks 

Swallowing start - 10-12 weeks 

External genital formed-12 weeks 

Urine formation -12 weeks 

Breathing movement- 11 weeks

Bleeding during implantation in uterus – heartman’s sign

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