ABORTION

 Definition: - It is termination of pregnancy (expulsion or extraction) of embryo before 22 week or below 500 gm weight of fetus 

                                                 or

Expulsion From the uterus either internally or accidentally 

Fetus weight less than 500 gm  

It is before 22 weeks of gestation 

ABORTION TYPE

                          Spontaneous     Induced 

Isolated     Recurrent            Legal   Iliegal 

(Sporadic)    (Habitual) (MTP)           (Criminal)

         Septic  

                                                                                           comman            

Threatened 

Inevitable 

Complete

In Complete 

Missed 

Septic (less Common)

Incidence :- 10-20%

Common course of Abortions :-

Fetal factor :-

Chromosomal abnormalities (Genetic Factor)

Abortions in 1st trimester

(50-75% cases) 

15% Cases            50% are due to defect in 

 due to defect in Paternal (father) Gametogenesis 

Maternal gametogenesis

 Genetic factor: - Autosomal trisomy (22%)

                                  Monosomy (11%) Trisomy- chromosome pase 

Poly Peptide (10%)  (3or more) x 

 Endocrine a metabolic factor :-

Lacteal Phase defect 

Progesterone deficiency 

Thyroid disease 

DM

 Anatomical Abnormalities :-

Cervical in competence 

Congenital Malformation of uterus 

Uterine Fibroid 

Ashesman syndrome 

 Infections :-

Viral, Rubella mepatomegalo HIV

Parasitic Malaria 

Bacterial Chlamydia, bra celli

 Immunological disorder :-

Auto immune disease 

Maternal illness 

Blood group incompatibility :-

Environmental Factor :-

Smoking 

Alcohol intake 

Exposure to radiation 

Drugs, chemical 

IUD,S